Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 13/20 | 0.61 |
| ▸ | NSD2 | O96028 | 2/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.59 |
| ▸ | CTRC | Q99895 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346557 | 0.87 | NSD2 (0.76) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL3346242 | 0.82 | CYP1A2 (0.73) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL3345918 | 0.79 | CTRB1 (0.58) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL3347554 | 0.79 | KMT2A (0.57) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL14580408 | 0.78 | CYP1A2 (0.60) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL5701120 | 0.77 | CTRB1 (0.73) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL30049470 | 0.77 | CTRB1 (0.73) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL6763835 | 0.77 | CTRB1 (0.73) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL28551711 | 0.77 | CYP1A2 (0.70) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL15115349 | 0.77 | CYP1A2 (0.70) | MPLNSD2MMP14CASP6CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | claimed |
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | disclosed |