Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.33 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.33 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346817 | 0.84 | DYRK1A (0.41) | DYRK1AOGADHFRCYP19A1TGFBR1 | |
| SCHEMBL3346876 | 0.82 | CYP19A1 (0.42) | CYP19A1 | |
| SCHEMBL3345949 | 0.81 | GRM5 (0.42) | GRM5 | |
| SCHEMBL3347519 | 0.80 | GRM4 (0.46) | DYRK1AGRM5 | |
| SCHEMBL3347027 | 0.75 | GRM5 (0.50) | DYRK1AGRM5TGFBR1 | |
| SCHEMBL3346390 | 0.75 | DYRK1A (0.36) | DYRK1AGRM5SCN5A | |
| SCHEMBL3416442 | 0.74 | KCNH2 (0.41) | DYRK1AGRM5OGAFFAR1FFAR4 | |
| SCHEMBL3346551 | 0.72 | DYRK1A (0.35) | DYRK1AOGASCN5ATGFBR1 | |
| SCHEMBL3347276 | 0.72 | DYRK1A (0.35) | DYRK1AGRM5OGADHFRSCN5A | |
| SCHEMBL3347789 | 0.72 | GRM5 (0.49) | DYRK1AGRM5OGASCN5ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |