Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347261 | 0.83 | GRM5 (0.47) | — | |
| SCHEMBL3348379 | 0.82 | CYP11B1 (0.38) | CYP11B1CYP11B2IDH1NOS1ALDH1A1 | |
| SCHEMBL3346817 | 0.82 | DYRK1A (0.41) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3345883 | 0.82 | DYRK1A (0.37) | CYP19A1 | |
| SCHEMBL3345949 | 0.80 | GRM5 (0.42) | IDH1ALDH1A1 | |
| SCHEMBL3345830 | 0.78 | FFAR1 (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL3346993 | 0.75 | GRM5 (0.51) | — | |
| SCHEMBL2177472 | 0.73 | DYRK1A (0.44) | ALDH1A1 | |
| SCHEMBL3347519 | 0.71 | GRM4 (0.46) | ALDH1A1 | |
| SCHEMBL3346985 | 0.71 | GRM5 (0.42) | IDH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |