Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346885 | 0.81 | OGA (0.38) | DYRK1AOGAPCSK9TGFBR1SCN5A | |
| SCHEMBL3347519 | 0.76 | GRM4 (0.46) | DYRK1AGRM5SMN1; SMN2 | |
| SCHEMBL3345883 | 0.72 | DYRK1A (0.37) | DYRK1AKCNN3OGADHFRGRM5 | |
| SCHEMBL3346551 | 0.72 | DYRK1A (0.35) | DYRK1AOGAPCSK9TGFBR1SCN5A | |
| SCHEMBL3347027 | 0.72 | GRM5 (0.50) | DYRK1AGRM5TGFBR1 | |
| SCHEMBL3346192 | 0.71 | GRM5 (0.47) | DYRK1AOGAGRM5TGFBR1SCN5A | |
| SCHEMBL3346766 | 0.71 | GRM5 (0.53) | GRM5TGFBR1SMN1; SMN2 | |
| SCHEMBL3346897 | 0.70 | FLT4 (0.39) | DYRK1AOGAPCSK9TGFBR1SCN5A | |
| SCHEMBL3347627 | 0.70 | OGA (0.38) | DYRK1AOGAPCSK9TGFBR1SCN5A | |
| SCHEMBL3346384 | 0.70 | GRM5 (0.43) | DYRK1AOGAGRM5TGFBR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |