Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | MPL | P40238 | 7/20 | 0.56 |
| ▸ | CTRC | Q99895 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPRA | P18433 | 1/20 | 0.56 |
| ▸ | PTPRB | P23467 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30049470 | 0.88 | CTRB1 (0.73) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL5701120 | 0.88 | CTRB1 (0.73) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL6763835 | 0.88 | CTRB1 (0.73) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL3345918 | 0.87 | CTRB1 (0.58) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL2118271 | 0.87 | CTRB1 (0.71) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL10625282 | 0.87 | CTRB1 (0.71) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL30960384 | 0.87 | CTRB1 (0.71) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL9577795 | 0.87 | CTRB1 (0.71) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL31511329 | 0.86 | THRB (0.56) | MAPK1ALDH1A1CTRB1CYP1A2MPL | |
| SCHEMBL10621005 | 0.86 | CYP1A2 (0.70) | MAPK1ALDH1A1CTRB1CYP1A2MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | claimed |
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | disclosed |