Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 5/20 | 0.54 |
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455404 | 0.87 | GLS (0.54) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL16181822 | 0.87 | GLS (0.55) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL8342682 | 0.87 | GLS (0.55) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL1165088 | 0.87 | GLS (0.55) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL30069429 | 0.87 | GLS (0.55) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL13981921 | 0.87 | GLS (0.55) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL25908275 | 0.86 | GLS (0.50) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL5102152 | 0.85 | GLS (0.54) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL184953 | 0.85 | GLS (0.54) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL851272 | 0.85 | GLS (0.55) | GLSBRD4KDM4ACREBBPNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |