SCHEMBL184953

SCHEMBL184953

CC(C)(C)OC(=O)NCc1cccc(CN)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLS O94925 5/20 0.54
KDM4A O75164 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
BRD4 O60885 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2D6 P10635 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
ACACB O00763 2/20 0.47
ACACA Q13085 2/20 0.47
CYP3A4 P08684 1/20 0.47
CREBBP Q92793 1/20 0.47
NAMPT P43490 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA7 P43166 1/20 0.45
CA14 Q9ULX7 1/20 0.45
HTR2C P28335 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31609012 0.99 GLS (0.53) GLSKDM4ALOXL2BRD4CYP1A2
SCHEMBL15656811 0.89 GLS (0.53) GLSKDM4ABRD4CREBBPNAMPT
SCHEMBL27113184 0.89 AOC3 (0.56) GLSKDM4ABRD4CYP3A4CREBBP
SCHEMBL27113191 0.88 KDM4A (0.46) GLSKDM4AACACBACACANAMPT
SCHEMBL99337 0.88 TPSAB1 (0.56) KDM4ALOXL2CYP1A2CYP2C9CYP2D6
SCHEMBL13981921 0.87 GLS (0.55) GLSKDM4ABRD4CYP3A4CREBBP
SCHEMBL16181822 0.87 GLS (0.55) GLSKDM4ABRD4CYP3A4CREBBP
SCHEMBL30069429 0.87 GLS (0.55) GLSKDM4ABRD4CYP3A4CREBBP
SCHEMBL1165088 0.87 GLS (0.55) GLSKDM4ABRD4CYP3A4CREBBP
SCHEMBL8342682 0.87 GLS (0.55) GLSKDM4ABRD4CREBBPNAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105030693-A Lung-targeting gelatin microsphere agent containing cefquinome sulfate and preparation method of lung-targeting gelatin microsphere agents UNIV QINGDAO AGRICULTURAL 2015-11-11 CN claimed
US-20260028342-A1 ENHANCING ANTIMETASTASIS ACTIVITY USING TARGETED PROTEIN DEGRADATION UNIV NORTH CAROLINA CHAPEL HILL (US) 2026-01-29 US disclosed
US-12479840-B2 HMG-CoA reductase degradation inducing compound UPPTHERA INC. (KR) 2025-11-25 US disclosed
EP-4536638-A2 INHIBITORS OF BACTERIAL TYPE III SECRETION SYSTEM Microbiotix, Inc. (US) 2025-04-16 EP disclosed
EP-4526303-A1 N6-ADENOSINE-METHYLTRANSFERASE PROTACS AND METHODS OF USE THEREOF University of Zurich (CH) 2025-03-26 EP disclosed
WO-2025049326-A1 TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 BIOCRYST PHARMACEUTICALS, INC. (US) 2025-03-06 WO disclosed
US-20250074904-A1 NSD2-TARGETED CHECMICAL DEGRADERTS AND COMPOSITIONS AND METHODS OF USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-03-06 US disclosed
CN-119487029-A N6-adenosyl-methyltransferase PROTAC and methods of use thereof 苏黎世大学 2025-02-18 CN disclosed
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SUPERTRANS MEDICAL LTD (IL) 2024-02-29 US disclosed
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SUPERTRANS MEDICAL LTD (IL) 2024-02-29 US disclosed
EP-0723438-A1 SUBSTITUTED UREA AND ISOTHIOUREA DERIVATIVES AS NO SYNTHASE INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1996-07-31 EP disclosed
WO-1996019440-A1 ACETAMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS FOR THE NITRIC OXIDE SYNTHASE THE WELLCOME FOUNDATION LIMITED (GB) 1996-06-27 WO disclosed
WO-1995032945-A1 COMPOSITIONS AND METHODS FOR TREATING MAST-CELL MEDIATED CONDITIONS ARRIS PHARMACEUTICAL CORPORATION (US) 1995-12-07 WO disclosed
EP-0674623-A1 BICYCLIC FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1995-10-04 EP disclosed
EP-0672658-A1 Antithrombotic agents ELI LILLY AND COMPANY (US) 1995-09-20 EP disclosed
WO-1995023609-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed
WO-1995009619-A2 SUBSTITUTED UREA AND ISOTHIOUREA DERIVATIVES AS NO SYNTHASE INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1995-04-13 WO disclosed
CN-1094718-A Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORP (US) 1994-11-09 CN disclosed
WO-1994014776-A2 BICYCLIC FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1994-07-07 WO disclosed
US-4624943-A Aromatic basic-tailed vasopressin antagonists SMITHKLINE BECKMAN CORPORATION (US) 1986-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028342-A1 ENHANCING ANTIMETASTASIS ACTIVITY USING TARGETED PROTEIN DEGRADATION EEF1A2, EEF1E1, EEF1D GLS 2439/4885KDM4A 3690/4885LOXL2 2257/4885
US-20250074904-A1 NSD2-TARGETED CHECMICAL DEGRADERTS AND COMPOSITIONS AND METHODS OF USE THEREOF NCOR2, NSD2, NCOR1 GLS 4538/4885KDM4A 343/4885LOXL2 1638/4885
US-12479840-B2 HMG-CoA reductase degradation inducing compound HMGCR, HMGB2, LDLR GLS 1762/4885KDM4A 766/4885LOXL2 429/4885
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SLC7A1, ABCB11, SLC1A5 GLS 230/4885KDM4A 4030/4885LOXL2 3259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.