Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2260765 | 0.79 | KDM4D (0.40) | KMT2AWDR5KDM4EKDM4DSMN1; SMN2 | |
| SCHEMBL3350173 | 0.77 | KDM4D (0.52) | HCAR3HCAR2KDM4EKDM4DEGLN1 | |
| SCHEMBL18360158 | 0.74 | HCAR3 (0.49) | HCAR3HCAR2KMT2AMEN1KDM4E | |
| SCHEMBL15295907 | 0.74 | HCAR3 (0.49) | HCAR3HCAR2KMT2AMEN1KDM4E | |
| SCHEMBL2259073 | 0.72 | PTGS2 (0.41) | KMT2AWDR5KDM4DSMN1; SMN2ALDH1A1 | |
| SCHEMBL5586094 | 0.72 | HCAR3 (0.44) | HCAR3HCAR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6079761 | 0.72 | HCAR3 (0.51) | HCAR3KDM4DEGLN1ALDH1A1CTRC | |
| SCHEMBL11676816 | 0.70 | HCAR3 (0.54) | HCAR3KDM4DSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20186697 | 0.70 | HPGD (0.51) | KDM4ETDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5159054 | 0.69 | HCAR3 (0.38) | HCAR3HCAR2KDM4EGLP1RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |