Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 3/20 | 0.35 |
| ▸ | PLAU | P00749 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729333 | 0.87 | MAOB (0.34) | MEN1KMT2APPARDMAOBMAOA | |
| SCHEMBL3192337 | 0.85 | PRSS1 (0.52) | PLGPLAUPRSS1PRMT1F2 | |
| SCHEMBL727965 | 0.84 | PRMT1 (0.53) | PLGPLAUPRSS1PRMT1F2 | |
| Hydrochloric Acid SCHEMBL3241146 | 0.83 | PRSS1 (0.54) | PLGPLAUPRSS1PRMT1F2 | |
| SCHEMBL727332 | 0.80 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL727593 | 0.79 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL11936601 | 0.78 | MEN1 (0.38) | MEN1KMT2APLGPLAUPRSS1 | |
| SCHEMBL729234 | 0.77 | MEN1 (0.38) | MEN1KMT2APLGPLAUPRSS1 | |
| SCHEMBL3346077 | 0.77 | GAA (0.51) | MEN1KMT2APLGPLAUPRSS1 | |
| SCHEMBL12213750 | 0.77 | CYP19A1 (0.45) | MEN1KMT2ACYP2D6HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242152-B2 | Use of 4-[(4-thiazolyl)phenoxy]alkoxy-benzamidine derivatives for the prophylaxis and treatment of osteoporosis | DONG WHA PHARMACEUTICAL CO., LTD. (KR) | 2012-08-14 | — | — | US | disclosed |
| US-20100160394-A1 | USE OF 4-[(4- THIAZOLYL)PHENOXY]ALKOXY-BENZAMIDINE DERIVATIVES FOR THE PROPHYLAXIS AND TREATMENT OF OSTEOPOROSIS | DONGWHA PHARMACEUTICAL CO., LTD. | 2010-06-24 | — | — | US | disclosed |
| EP-1411935-A4 | USE OF 4- (4-THIAZOLYL)PHENOXL] ALKOXY-BENZAMIDINE DERIVATIVES FOR TREATMENT OF OSTEOPOROSIS | DONG WHA PHARM IND CO LTD (KR) | 2005-11-09 | — | — | EP | disclosed |
| EP-1411935-A1 | USE OF 4- (4-THIAZOLYL)PHENOXL] ALKOXY-BENZAMIDINE DERIVATIVES FOR TREATMENT OF OSTEOPOROSIS | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003007947-A1 | USE OF 4-[(4-THIAZOLYL)PHENOXL] ALKOXY-BENZAMIDINE DERIVATIVES FOR TREATMENT OF OSTEOPOROSIS | DONG WHA PHARM. IND. CO., LTD. (KR) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160394-A1 | USE OF 4-[(4- THIAZOLYL)PHENOXY]ALKOXY-BENZAMIDINE DERIVATIVES FOR THE PROPHYLAXIS AND TREATMENT OF OSTEOPOROSIS | SOST, PTH1R, PTMS | MEN1 813/4885KMT2A 1027/4885PLG 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.