SCHEMBL19781323

SCHEMBL19781323

C[Si](C)(C)C#Cc1cc(F)c(Br)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.34
KDM1B Q8NB78 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7526965 0.83 LOX (0.31)
SCHEMBL19677742 0.81 HDAC1 (0.31)
SCHEMBL19781318 0.79
SCHEMBL20929147 0.79 LOX (0.32)
SCHEMBL19748358 0.79 KDM1A (0.33) KDM1AKDM1B
SCHEMBL31529670 0.77 LOX (0.33)
SCHEMBL1478000 0.77 LOX (0.35)
SCHEMBL14658440 0.76 ACACB (0.39)
SCHEMBL19781239 0.76 GABRA1 (0.31)
SCHEMBL19781320 0.76 TRPV4 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889610-B2 Alpha-D-galactoside inhibitors of galectins GALECTO BIOTECH AB (DK) 2021-01-12 US disclosed
US-20190315793-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2019-10-17 US disclosed
CN-109563119-A α-D- galactoside the inhibitor of galactose agglutinin 格莱克特生物技术公司 2019-04-02 CN disclosed
WO-2018011094-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2018-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315793-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS LGALS1, LGALS3, LGALS2 KDM1A 3404/4885KDM1B 4542/4885
US-10889610-B2 Alpha-D-galactoside inhibitors of galectins LGALS1, LGALS3, LGALS2 KDM1A 3404/4885KDM1B 4542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.