Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635547 | 1.00 | CES2 (0.47) | CES2MGLLTSHRMAPK1NPSR1 | |
| SCHEMBL2761134 | 0.83 | TSHR (0.50) | CES2MGLLTSHRMAPK1NPSR1 | |
| SCHEMBL10893016 | 0.83 | TSHR (0.50) | CES2MGLLTSHRMAPK1NPSR1 | |
| Methyl Alcohol SCHEMBL9419583 | 0.82 | TSHR (0.58) | CES2MGLLTSHRMAPK1NPSR1 | |
| SCHEMBL23590587 | 0.79 | TSHR (0.52) | CES2MGLLTSHRMAPK1ALDH1A1 | |
| SCHEMBL5327271 | 0.79 | TSHR (0.52) | CES2MGLLTSHRMAPK1ALDH1A1 | |
| SCHEMBL5323279 | 0.79 | TSHR (0.52) | CES2MGLLTSHRMAPK1ALDH1A1 | |
| SCHEMBL7230332 | 0.79 | KCNN4 (0.48) | CES2NPSR1ALDH1A1GAAPOLB | |
| SCHEMBL62723 | 0.79 | TSHR (0.67) | CES2MGLLTSHRMAPK1NPSR1 | |
| SCHEMBL25485520 | 0.79 | HTT (0.48) | CES2MGLLTSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | disclosed |