Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.46 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349846 | 0.89 | ROCK2 (0.48) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL13365119 | 0.84 | HPGD (0.49) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL3346381 | 0.84 | SSTR4 (0.51) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL3346230 | 0.84 | KCNQ3 (0.66) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL3346373 | 0.83 | KCNH2 (0.57) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL3346539 | 0.83 | KCNH2 (0.57) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL13365126 | 0.83 | KCNH2 (0.52) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL3353138 | 0.82 | KCNQ3 (0.52) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL13365131 | 0.81 | KCNQ3 (0.47) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 | |
| SCHEMBL3346676 | 0.81 | KCNQ3 (0.53) | KCNQ3KCNQ2RECQLKCNH2KCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |