Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499191 | 0.92 | MAPT (0.62) | GAAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL3346477 | 0.87 | SMN1; SMN2 (0.58) | GAAMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL62508 | 0.83 | HPGD (0.57) | MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL12987073 | 0.81 | — | — | |
| SCHEMBL7508338 | 0.81 | — | — | |
| SCHEMBL8259432 | 0.81 | ALDH1A1 (0.58) | GAAALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL1720494 | 0.81 | MAPT (0.72) | GAAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL19682978 | 0.81 | SMN1; SMN2 (0.75) | MAPTHTTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL25194096 | 0.78 | GAA (0.41) | GAAMAPTALDH1A1HTTTDP1 | |
| SCHEMBL2911286 | 0.77 | ALDH1A1 (0.48) | GAAALDH1A1HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887520-A1 | ANTIBACTERIAL ANTISENSE AGENTS | Pedanius Therapeutics Limited (GB) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109792-A1 | ANTIBACTERIAL ANTISENSE AGENTS | Pedanius Therapeutics Limited (GB) | 2020-06-04 | — | — | WO | disclosed |
| WO-2010053732-A1 | ISOINDOLINE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | CELGENE CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |