Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158 | 0.96 | — | — | |
| SCHEMBL2757577 | 0.96 | — | — | |
| SCHEMBL17078009 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL11574766 | 0.93 | — | — | |
| Fluoride SCHEMBL752724 | 0.93 | ACHE (0.57) | — | |
| Hydrochloric Acid SCHEMBL17559514 | 0.93 | — | — | |
| Fluoride SCHEMBL752726 | 0.93 | ACHE (0.57) | — | |
| SCHEMBL10634092 | 0.93 | — | — | |
| Fluoride SCHEMBL4233421 | 0.93 | — | — | |
| Phosphine SCHEMBL11574538 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005794-B2 | Production method for 2-fluoro-4-borono-L-phenylalanine, and precursor of 2-fluoro-4-borono-L-phenylalanine | STELLA PHARMA CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20160311836-A1 | PRODUCTION METHOD FOR 2-FLUORO-4-BORONO-L-PHENYLALANINE, AND PRECURSOR OF 2-FLUORO-4-BORONO-L-PHENYLALANINE | STELLA PHARMA CORPORATION (JP) | 2016-10-27 | — | — | US | disclosed |
| CN-104870422-A | Novel amine derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |