Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347547 | 0.82 | GRM5 (0.54) | GRM5CYP1A2DYRK1AOGA | |
| SCHEMBL3347098 | 0.80 | DYRK1A (0.33) | GRM5CYP1A2DYRK1AOGASCN5A | |
| SCHEMBL3350895 | 0.80 | GRM5 (0.36) | GRM5CYP1A2DYRK1AOGASCN5A | |
| SCHEMBL3346736 | 0.79 | OGA (0.35) | GRM5CYP1A2DYRK1AOGA | |
| SCHEMBL3347868 | 0.74 | GRM5 (0.61) | GRM5 | |
| SCHEMBL3346587 | 0.74 | RARB (0.40) | DYRK1AOGA | |
| SCHEMBL3347519 | 0.72 | GRM4 (0.46) | GRM5CYP1A2DYRK1ANPC1RAB9A | |
| SCHEMBL9903641 | 0.72 | CYP1A2 (0.48) | GRM5CYP1A2FFAR1NPC1RAB9A | |
| SCHEMBL3348318 | 0.71 | GRM5 (0.43) | GRM5OGA | |
| SCHEMBL3347143 | 0.71 | OGA (0.39) | GRM5DYRK1AOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |