Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346711 | 0.79 | GRM5 (0.52) | OGADYRK1ACYP1A2GRM5 | |
| SCHEMBL3347098 | 0.78 | DYRK1A (0.33) | OGADYRK1ACYP1A2GRM5 | |
| SCHEMBL3347547 | 0.77 | GRM5 (0.54) | OGADYRK1ACYP1A2GRM5 | |
| SCHEMBL9903247 | 0.73 | KIT (0.39) | — | |
| SCHEMBL3350895 | 0.73 | GRM5 (0.36) | OGADYRK1ACYP1A2GRM5 | |
| SCHEMBL4861900 | 0.71 | GRM5 (0.60) | CYP1A2GRM5 | |
| SCHEMBL3347519 | 0.70 | GRM4 (0.46) | DYRK1ACYP1A2GRM5 | |
| SCHEMBL3347789 | 0.69 | GRM5 (0.49) | OGADYRK1ACYP1A2GRM5 | |
| SCHEMBL3347027 | 0.69 | GRM5 (0.50) | DYRK1ACYP1A2GRM5 | |
| SCHEMBL3348818 | 0.69 | GRM5 (0.47) | OGADYRK1AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |