Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347868 | 0.81 | GRM5 (0.61) | GRM5 | |
| SCHEMBL3346711 | 0.80 | GRM5 (0.52) | GRM5OGADYRK1ACYP1A2SCN5A | |
| SCHEMBL3347098 | 0.76 | DYRK1A (0.33) | GRM5OGAFGFR2DYRK1ACYP1A2 | |
| SCHEMBL3347547 | 0.75 | GRM5 (0.54) | GRM5OGADYRK1ACYP1A2 | |
| SCHEMBL3346736 | 0.73 | OGA (0.35) | GRM5OGADYRK1ACYP1A2 | |
| SCHEMBL7417628 | 0.72 | GRM5 (0.60) | GRM5CYP1A2 | |
| SCHEMBL3347519 | 0.71 | GRM4 (0.46) | GRM5DYRK1ACYP1A2 | |
| SCHEMBL4160148 | 0.71 | GRM5 (0.65) | GRM5CYP1A2 | |
| SCHEMBL3348318 | 0.70 | GRM5 (0.43) | GRM5OGAFGFR2 | |
| SCHEMBL15719787 | 0.70 | DYRK1A (0.44) | OGADYRK1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |