Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346877 | 0.82 | GRM5 (0.52) | GRM5DYRK1A | |
| SCHEMBL3346505 | 0.82 | GRM5 (0.55) | GRM5DYRK1A | |
| SCHEMBL3346202 | 0.81 | GRM5 (0.57) | GRM5 | |
| SCHEMBL3345958 | 0.81 | GRM5 (0.52) | GRM5 | |
| SCHEMBL3347563 | 0.81 | GRM5 (0.36) | GRM5DYRK1A | |
| SCHEMBL3347789 | 0.79 | GRM5 (0.49) | GRM5DYRK1AOGA | |
| SCHEMBL3347519 | 0.77 | GRM4 (0.46) | GRM5DYRK1A | |
| SCHEMBL3346432 | 0.77 | GRM5 (0.41) | GRM5OGA | |
| SCHEMBL3346384 | 0.73 | GRM5 (0.43) | GRM5DYRK1AOGA | |
| SCHEMBL3346603 | 0.73 | GRM5 (0.41) | GRM5DYRK1AOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |