Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346202 | 0.81 | GRM5 (0.57) | GRM5PIK3CD | |
| SCHEMBL3346754 | 0.77 | GRM5 (0.45) | GRM5OGA | |
| SCHEMBL3714223 | 0.75 | ALDH1A1 (0.62) | GRM5ATMALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL3346877 | 0.75 | GRM5 (0.52) | GRM5 | |
| SCHEMBL3346505 | 0.75 | GRM5 (0.55) | GRM5ALDH1A1 | |
| SCHEMBL1477039 | 0.74 | MAPT (0.55) | GRM5ATMALDH1A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL1477229 | 0.73 | MAPT (0.54) | GRM5ATMALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL3345958 | 0.73 | GRM5 (0.52) | GRM5 | |
| SCHEMBL25047246 | 0.73 | ATM (0.46) | GRM5ATMALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL3347498 | 0.73 | GRM5 (0.41) | GRM5PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |