Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.30 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.30 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346502 | 0.91 | CDK2 (0.36) | S100A4RAD52KCNN1KCNN2KCNN3 | |
| SCHEMBL3348367 | 0.90 | CDK2 (0.33) | KCNN1KCNN2KCNN3 | |
| SCHEMBL3351303 | 0.89 | KCNN1 (0.30) | KCNN1KCNN2KCNN3 | |
| SCHEMBL3346750 | 0.88 | PDE10A (0.32) | PDE10AKCNN1KCNN2KCNN3 | |
| SCHEMBL3351756 | 0.88 | CCNE1 (0.34) | — | |
| SCHEMBL3347657 | 0.88 | CCNE1 (0.33) | — | |
| SCHEMBL3346918 | 0.77 | DYRK1A (0.41) | S100A4RAD52 | |
| SCHEMBL3347071 | 0.67 | CYP2A6 (0.32) | PDE10AKCNN1KCNN2KCNN3 | |
| SCHEMBL3346532 | 0.67 | CDK2 (0.38) | PDE10AKCNN3 | |
| SCHEMBL7902940 | 0.67 | PDE10A (0.35) | PDE10AKCNN1KCNN2KCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |