Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | PER2 | O15055 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15652050 | 0.77 | LRRK2 (0.51) | LRRK2F10PRKDCMTOR | |
| SCHEMBL18631136 | 0.75 | HTT (0.44) | LRRK2 | |
| SCHEMBL5512937 | 0.74 | F10 (0.51) | F10MTOR | |
| SCHEMBL8306339 | 0.73 | ALDH1A1 (0.45) | LRRK2F10PRKDC | |
| SCHEMBL77406 | 0.71 | MAPT (0.43) | LRRK2F10TSHR | |
| SCHEMBL18630668 | 0.71 | F10 (0.54) | F10HTR1A | |
| SCHEMBL5516270 | 0.71 | F10 (0.43) | F10MTOR | |
| SCHEMBL5509755 | 0.71 | F10 (0.43) | F10MTOR | |
| SCHEMBL25653902 | 0.71 | CRBN (0.48) | KDM4ETSHRP2RX7 | |
| SCHEMBL25033227 | 0.71 | PTGS2 (0.46) | LRRK2F10MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |