Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18589104 | 0.98 | POLB (0.59) | POLB | |
| SCHEMBL13970818 | 0.98 | POLB (0.59) | POLB | |
| SCHEMBL3345547 | 0.98 | POLB (0.59) | POLB | |
| SCHEMBL3345587 | 0.92 | TYMS (0.66) | TYMS | |
| SCHEMBL16716006 | 0.89 | POLB (0.57) | POLB | |
| SCHEMBL30807962 | 0.89 | POLB (0.49) | POLB | |
| SCHEMBL2515240 | 0.88 | POLB (0.59) | POLBTYMS | |
| SCHEMBL14930108 | 0.88 | POLB (0.59) | POLBTYMS | |
| SCHEMBL10046513 | 0.88 | POLB (0.59) | POLBTYMS | |
| SCHEMBL8600188 | 0.88 | POLB (0.56) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292135-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-18 | — | — | US | claimed |
| EP-1874801-A4 | INHIBITORS OF RECA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | UNIV NORTH CAROLINA (US) | 2009-03-25 | — | — | EP | claimed |
| EP-1874801-A2 | INHIBITORS OF RECA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | The University of North Carolina at Chapel Hill (US) | 2008-01-09 | — | — | EP | claimed |
| WO-2006096757-A2 | INHIBITORS OF RECA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-09-14 | — | — | WO | claimed |
| US-20060199768-A1 | Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2006-09-07 | — | — | US | claimed |
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2012-05-31 | — | — | US | disclosed |
| US-20100292135-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-18 | — | — | US | disclosed |
| WO-2009154828-A9 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-05-06 | — | — | WO | disclosed |
| WO-2009154828-A2 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-12-23 | — | — | WO | disclosed |
| EP-1874801-A4 | INHIBITORS OF RECA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | UNIV NORTH CAROLINA (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1874801-A2 | INHIBITORS OF RECA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | The University of North Carolina at Chapel Hill (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006096757-A2 | INHIBITORS OF RECA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-09-14 | — | — | WO | disclosed |
| US-20060199768-A1 | Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199768-A1 | Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens | RECQL, DNA2, WRN | POLB 87/4885TYMS 316/4885 |
| US-20100292135-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | RECQL, DNA2, WRN | POLB 87/4885TYMS 316/4885 |
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | RECQL, WRN, ADAR | POLB 252/4885TYMS 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.