SCHEMBL334717

SCHEMBL334717

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)OCc1ccccc1)C(=O)N[C@H](CNC(=O)[C@H](O)Cc1ccccc1)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PSMB1 P20618 1/20 0.53
NPY4R P50391 9/20 0.52
NPY1R P25929 5/20 0.52
NPY2R P49146 3/20 0.50
NPY5R Q15761 3/20 0.50
CAPN1 P07384 3/20 0.50
CTSL P07711 2/20 0.49
CTSK P43235 1/20 0.49
CAPN2 P17655 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334368 1.00 PSMB1 (0.53) PSMB1NPY4RNPY1RNPY2RNPY5R
SCHEMBL334649 0.92 NPY4R (0.51) PSMB1NPY4RNPY1RNPY2RNPY5R
SCHEMBL335508 0.92 NPY4R (0.51) PSMB1NPY4RNPY1RNPY2RNPY5R
SCHEMBL334080 0.91 NPY4R (0.54) PSMB1NPY4RNPY1RNPY2RNPY5R
SCHEMBL334603 0.91 NPY4R (0.54) PSMB1NPY4RNPY1RNPY2RNPY5R
SCHEMBL13155522 0.91 NPY4R (0.54) PSMB1NPY4RNPY1RNPY2RNPY5R
SCHEMBL335148 0.89 CAPN1 (0.52) PSMB1NPY4RNPY1RNPY2RNPY5R
SCHEMBL4450750 0.88 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5RCAPN1
SCHEMBL4445591 0.88 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5RCAPN1
SCHEMBL10027648 0.88 CAPN1 (0.55) PSMB1NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097582-B2 Peptide derivatives useful as antimicrobial agents and for treating wounds NEOBIOTICS AB (SE) 2012-01-17 US disclosed
US-8097582-B2 Peptide derivatives useful as antimicrobial agents and for treating wounds NEOBIOTICS AB (SE) 2012-01-17 US disclosed
US-8097582-B2 Peptide derivatives useful as antimicrobial agents and for treating wounds NEOBIOTICS AB (SE) 2012-01-17 US disclosed
US-20090118198-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS ZULA DIAGNOSTICS AB (SE) 2009-05-07 US disclosed
US-20090118198-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS ZULA DIAGNOSTICS AB (SE) 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118198-A1 NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS VIP, NGLY1, ARG1 PSMB1 1943/4885NPY4R 488/4885NPY1R 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.