Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | OTC | P00480 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346616 | 1.00 | GPR84 (0.45) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL11240271 | 0.94 | GPR84 (0.48) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL3351368 | 0.84 | GPR84 (0.42) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL28586986 | 0.84 | GPR84 (0.42) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL11229239 | 0.84 | GPR84 (0.42) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL18125979 | 0.83 | GPR84 (0.48) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL26525742 | 0.80 | C3AR1 (0.37) | C3AR1OTCMEN1GAAKMT2A | |
| L-Citrulline SCHEMBL319675 | 0.79 | OTC (0.48) | OTCMEN1KMT2ADDAH1SMN1; SMN2 | |
| L-Citrulline SCHEMBL31672873 | 0.79 | OTC (0.48) | OTCMEN1KMT2ADDAH1SMN1; SMN2 | |
| L-Citrulline SCHEMBL319676 | 0.79 | OTC (0.48) | OTCMEN1KMT2ADDAH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326993-B1 | PRODUCTION OF ALPHA-HYDROXY-CARBOXYLIC ACIDS USING A COUPLED ENZYME SYSTEM | EXCELSYN MOLECULAR DEV LTD (GB) | 2007-05-23 | — | — | EP | claimed |
| US-20040053382-A1 | Production of alpha-hydroxy-carboxylic acids using a coupled enzyme system | EXCELSYN MOLECULAR DEVELOPMENT LIMITED (GB) | 2004-03-18 | — | — | US | claimed |
| EP-1326993-A2 | PRODUCTION OF g(a)-HYDROXY-CARBOXYLIC ACIDS USING A COUPLED ENZYME SYSTEM | PCBU Services, Inc. (US) | 2003-07-16 | — | — | EP | claimed |
| WO-2002033110-A2 | PRODUCTION OF α-HYDROXY-CARBOXYLIC ACIDS USING A COUPLED ENZYME SYSTEM | PCBU SERVICES, INC. (US) | 2002-04-25 | — | — | WO | claimed |
| WO-2010060479-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY | POLYPHOR AG (CH) | 2010-06-03 | — | — | WO | disclosed |