⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038331 | 0.81 | ALDH1A1 (0.40) | — | |
| SCHEMBL10676884 | 0.79 | — | — | |
| SCHEMBL11509378 | 0.77 | — | — | |
| SCHEMBL2141079 | 0.77 | — | — | |
| SCHEMBL10753528 | 0.75 | — | — | |
| SCHEMBL11509212 | 0.75 | — | — | |
| SCHEMBL11193609 | 0.74 | — | — | |
| SCHEMBL1085729 | 0.73 | — | — | |
| SCHEMBL5528129 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL4813094 | 0.71 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459369-A | Synthetic method of N-Boc-vinyl glycine methyl ester and isomer thereof | 成都师范学院 | 2024-08-09 | — | — | CN | disclosed |
| US-20100137258-A1 | THIOPHOSPHI(O)NIC ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-06-03 | — | — | US | disclosed |
| EP-2183258-A2 | THIOPHOSPHI(O)NIC ACID DERIVATIVES AND THEIR USE AS AGONISTS OR ANTAGONISTS FOR METABOTROPIC GLUTAMATE RECEPTORS | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009016520-A2 | THIOPHOSPHI(O)NIC ACID DERIVATIVES AND THEIR USE AS AGONISTS OR ANTAGONISTS FOR METABOTROPIC GLUTAMATE RECEPTORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-02-05 | — | — | WO | disclosed |
| CN-101331143-A | Hypophosphorous acid derivatives and their therapeutic use | CENTRE NAT RECH SCIENT (FR) | 2008-12-24 | — | — | CN | disclosed |
| EP-1937699-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |
| CN-1107068-C | 2-amino-7-(1-substituted-2-hydroxyethyl)-3,5-dihydro-pyrrolo (3,2-D] pyrimidine-4-ones | NOVARTIS AG (CH) | 2003-04-30 | — | — | CN | disclosed |
| CN-1257503-A | 2-amino-7-(1-substituted-2-hydroxyethyl)-3,5-dihydro-pyrrolo (3,2-D] pyrimidine-4-ones | NOVARTIS AG (CH) | 2000-06-21 | — | — | CN | disclosed |
| EP-0529601-B1 | Process for the production of optically active vinylglycine in free or protected form by an enzymatic, enantioselective hydrolysis | HOECHST AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| EP-0256763-B1 | Process for azetidinones | UNIV NOTRE DAME DU LAC (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0529601-A1 | Process for the production of optically active vinylglycine in free or protected form by an enzymatic, anantioselective hydrolysis | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-03 | — | — | EP | disclosed |
| US-4751296-A | WITH POSITIVE HALOGEN IN THE PRESENCE OF WEAK BASE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0256763-A1 | Process for azetidinones | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-02-24 | — | — | EP | disclosed |