Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19723775 | 0.83 | ADH1B (0.41) | ALDH1A1LMNATET2TSHRRECQL | |
| SCHEMBL2361759 | 0.82 | TSHR (0.50) | ALDH1A1LMNATET2TSHRRECQL | |
| SCHEMBL3347778 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL15855934 | 0.78 | TSHR (0.46) | ALDH1A1LMNATET2TSHRRECQL | |
| SCHEMBL13538038 | 0.74 | ALDH1A1 (0.61) | ALDH1A1LMNATET2TSHRRECQL | |
| SCHEMBL7364154 | 0.74 | ALDH1A1 (0.61) | ALDH1A1LMNATET2TSHRRECQL | |
| SCHEMBL18293019 | 0.74 | TSHR (0.42) | ALDH1A1LMNATET2TSHRRECQL | |
| SCHEMBL15865613 | 0.74 | GAA (0.50) | ALDH1A1LMNATET2TSHRRECQL | |
| SCHEMBL11509213 | 0.74 | — | — | |
| SCHEMBL8230419 | 0.73 | ALDH1A1 (0.65) | ALDH1A1LMNATET2TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |