Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347840 | 1.00 | MGLL (0.47) | MGLLS1PR1EPHX2TRPM8TRPV1 | |
| SCHEMBL2424131 | 0.89 | MGLL (0.48) | MGLLEPHX2USP30LMNAKMT2A | |
| SCHEMBL3353056 | 0.88 | KMT2A (0.50) | MGLLTRPM8TRPV1LMNAKMT2A | |
| SCHEMBL3353050 | 0.88 | KMT2A (0.50) | MGLLTRPM8TRPV1LMNAKMT2A | |
| SCHEMBL2427480 | 0.84 | EPHX2 (0.42) | MGLLEPHX2TRPM8TRPV1 | |
| SCHEMBL2427211 | 0.84 | EPHX2 (0.42) | MGLLEPHX2TRPM8TRPV1 | |
| SCHEMBL2420601 | 0.83 | USP7 (0.43) | MGLLS1PR1USP30LMNAKMT2A | |
| SCHEMBL2427483 | 0.83 | EPHX2 (0.41) | MGLLEPHX2TRPM8TRPV1 | |
| SCHEMBL13363342 | 0.82 | MGLL (0.41) | MGLLEPHX2TRPM8TRPV1 | |
| Hydrochloric Acid SCHEMBL2427020 | 0.82 | USP7 (0.42) | MGLLS1PR1USP30LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058318-A1 | 1-OXA-8-AZASPIRO [4, 5 ] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |