Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350900 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2MAPTMEN1NPC1RAB9A | |
| SCHEMBL3345835 | 0.59 | MAPT (0.40) | SMN1; SMN2MAPTMEN1NPC1RAB9A | |
| SCHEMBL31398170 | 0.53 | TGFBR1 (0.43) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL31398124 | 0.53 | TGFBR1 (0.50) | SMN1; SMN2MAPTMEN1NPC1RAB9A | |
| SCHEMBL15259631 | 0.51 | GRM5 (0.33) | — | |
| SCHEMBL15259633 | 0.51 | GRM5 (0.33) | — | |
| SCHEMBL2044650 | 0.51 | GAA (0.33) | MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL2044649 | 0.51 | GAA (0.33) | MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL2049795 | 0.50 | GAA (0.33) | KDM4E | |
| SCHEMBL2049793 | 0.50 | GAA (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |