Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346234 | 0.86 | MC4R (0.71) | MC4RTAAR1POLBGAAKCNH2 | |
| SCHEMBL3346376 | 0.83 | MC4R (0.63) | MC4RTAAR1POLBGAAKCNH2 | |
| SCHEMBL3346679 | 0.83 | MC4R (0.59) | MC4RTAAR1POLBGAAKCNH2 | |
| SCHEMBL3353142 | 0.82 | MC4R (0.62) | MC4RTAAR1POLBGAAALDH1A1 | |
| SCHEMBL22160722 | 0.81 | MC4R (0.63) | MC4RTAAR1POLBGAAALDH1A1 | |
| SCHEMBL22178785 | 0.81 | MC4R (0.63) | MC4RTAAR1POLBGAAALDH1A1 | |
| SCHEMBL22178784 | 0.81 | MC4R (0.63) | MC4RTAAR1POLBGAAALDH1A1 | |
| SCHEMBL22178742 | 0.81 | MC4R (0.88) | MC4RTAAR1POLBGAAALDH1A1 | |
| SCHEMBL3346236 | 0.81 | MC4R (0.65) | MC4RTAAR1POLBGAAKCNH2 | |
| SCHEMBL3346487 | 0.81 | MC4R (0.59) | MC4RTAAR1POLBGAAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |