Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353265 | 0.93 | MC4R (0.53) | MC4RTAAR1GLAALDH1A1 | |
| SCHEMBL3346679 | 0.91 | MC4R (0.59) | MC4RTAAR1GLAALDH1A1CASP1 | |
| SCHEMBL3346376 | 0.89 | MC4R (0.63) | MC4RTAAR1GLAALDH1A1CASP1 | |
| SCHEMBL3353136 | 0.88 | TAAR1 (0.50) | MC4RTAAR1GLAALDH1A1CASP1 | |
| SCHEMBL3346234 | 0.87 | MC4R (0.71) | MC4RTAAR1ALDH1A1POLBGAA | |
| SCHEMBL3347960 | 0.85 | CNR1 (0.52) | MC4RTAAR1GLAALDH1A1POLB | |
| SCHEMBL3349847 | 0.83 | MC4R (0.58) | MC4RTAAR1GLAALDH1A1CASP1 | |
| SCHEMBL3348167 | 0.82 | MC4R (0.60) | MC4RTAAR1ALDH1A1POLBGAA | |
| SCHEMBL3346447 | 0.82 | MC4R (0.63) | MC4RTAAR1GLAALDH1A1CASP1 | |
| SCHEMBL3410126 | 0.82 | MC4R (0.57) | MC4RTAAR1POLBGAATLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |