Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348321 | 0.80 | HTR2C (0.52) | SLC6A4ALDH1A1PTGER1LMNAHTT | |
| SCHEMBL31644088 | 0.78 | SLC6A4 (0.66) | SLC6A4CCR5ALDH1A1RAB9APTGER1 | |
| SCHEMBL368071 | 0.78 | SLC6A4 (0.66) | SLC6A4CCR5ALDH1A1RAB9APTGER1 | |
| SCHEMBL1447864 | 0.75 | SLC6A4 (0.59) | SLC6A4CCR5ALDH1A1RAB9AMAOB | |
| SCHEMBL30504080 | 0.75 | SLC6A4 (0.59) | SLC6A4CCR5ALDH1A1RAB9AMAOB | |
| SCHEMBL2060462 | 0.72 | SMPD1 (0.59) | SLC6A4CCR5ALDH1A1RAB9AMAOB | |
| SCHEMBL30601752 | 0.72 | SMPD1 (0.59) | SLC6A4CCR5ALDH1A1RAB9AMAOB | |
| SCHEMBL30124921 | 0.72 | SMPD1 (0.59) | SLC6A4CCR5ALDH1A1RAB9AMAOB | |
| SCHEMBL15726115 | 0.70 | SLC6A4 (0.54) | SLC6A4CCR5ALDH1A1RAB9APTGER1 | |
| SCHEMBL3724105 | 0.70 | MEN1 (0.59) | SLC6A4CCR5ALDH1A1RAB9APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | claimed |