Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348259 | 0.80 | SLC6A4 (0.48) | PTGER1SLC6A4ALDH1A1LMNAHTT | |
| SCHEMBL3350544 | 0.74 | HTR2C (0.54) | HTR2CHTR2BSLC6A4MEN1KMT2A | |
| SCHEMBL22894882 | 0.70 | PTGDR2 (0.58) | HTR2CHTR2BPTGER1SLC6A4MEN1 | |
| SCHEMBL13144443 | 0.70 | MRGPRX4 (0.68) | HTR2CHTR2BPTGER1SLC6A4MEN1 | |
| SCHEMBL17589345 | 0.70 | MRGPRX4 (0.66) | HTR2CHTR2BPTGER1SLC6A4MEN1 | |
| SCHEMBL27804382 | 0.69 | MEN1 (0.56) | HTR2CHTR2BPTGER1SLC6A4MEN1 | |
| SCHEMBL14871868 | 0.69 | CYP1A2 (0.56) | SLC6A4MEN1KMT2AATMLMNA | |
| SCHEMBL20064612 | 0.69 | SLC6A4 (0.56) | HTR2CHTR2BPTGER1SLC6A4MEN1 | |
| SCHEMBL27804380 | 0.69 | SLC6A4 (0.52) | HTR2CHTR2BPTGER1SLC6A4MEN1 | |
| SCHEMBL2283229 | 0.68 | HTR2C (1.00) | HTR2CHTR2BSLC6A4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059393-A1 | SEROTONIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-27 | — | — | WO | claimed |