Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351358 | 0.84 | CYP11B2 (0.40) | DHODHGRM5 | |
| SCHEMBL15674287 | 0.82 | ALOX5AP (0.51) | ALOX5APFEN1FFAR4NPC1RAB9A | |
| SCHEMBL3348429 | 0.81 | GRM5 (0.44) | ALOX5APFEN1LOXL2NAAABTK | |
| SCHEMBL3347568 | 0.78 | GRM5 (0.38) | ALOX5APFEN1FFAR4NPC1RAB9A | |
| SCHEMBL15674555 | 0.74 | ALOX5AP (0.52) | ALOX5APFEN1FFAR4NPC1RAB9A | |
| SCHEMBL29501268 | 0.72 | NPC1 (0.56) | ALOX5APFEN1FFAR4NPC1RAB9A | |
| SCHEMBL15674356 | 0.72 | NPC1 (0.56) | ALOX5APFEN1FFAR4NPC1RAB9A | |
| SCHEMBL3581826 | 0.69 | CYP11B2 (0.44) | — | |
| SCHEMBL852757 | 0.69 | GRM5 (0.43) | CA1GRM5 | |
| SCHEMBL26426502 | 0.69 | GRM5 (0.52) | NPC1RAB9ABTKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |