Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022887 | 0.88 | KMT2A (0.87) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL9051137 | 0.88 | CA1 (0.69) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL30738251 | 0.88 | CA1 (0.79) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL1820807 | 0.88 | CA12 (0.69) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL248400 | 0.88 | CA1 (0.79) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL23417617 | 0.87 | ALDH1A1 (0.77) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL5806403 | 0.87 | MAPT (0.68) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL5806407 | 0.87 | CA1 (0.68) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL23392535 | 0.87 | MAPT (0.77) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL6490406 | 0.87 | CA1 (0.68) | CA1CA2CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | claimed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |