Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23392535 | 0.88 | MAPT (0.77) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL23417617 | 0.88 | ALDH1A1 (0.77) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL1820807 | 0.87 | CA12 (0.69) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL30738251 | 0.87 | CA1 (0.79) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL248400 | 0.87 | CA1 (0.79) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL9051137 | 0.87 | CA1 (0.69) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL3348400 | 0.87 | CA1 (0.69) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL4022887 | 0.87 | KMT2A (0.87) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL3351879 | 0.85 | CA12 (0.68) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL5806407 | 0.85 | CA1 (0.68) | MAPTCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |