Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351686 | 0.84 | GRM5 (0.49) | GRM5KCNH2DYRK1A | |
| SCHEMBL3346980 | 0.83 | GRM5 (0.49) | GRM5 | |
| SCHEMBL3347261 | 0.83 | GRM5 (0.47) | GRM5 | |
| SCHEMBL3347295 | 0.83 | GRM5 (0.48) | GRM5DYRK1A | |
| SCHEMBL3346805 | 0.83 | DYRK1A (0.43) | GRM5DYRK1A | |
| SCHEMBL3347519 | 0.82 | GRM4 (0.46) | GRM5DYRK1A | |
| SCHEMBL3345830 | 0.80 | FFAR1 (0.40) | GRM5DYRK1A | |
| SCHEMBL3347573 | 0.80 | GRM5 (0.58) | GRM5 | |
| SCHEMBL3351351 | 0.80 | FFAR1 (0.39) | GRM5DYRK1A | |
| SCHEMBL3346835 | 0.80 | GRM5 (0.50) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |