Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346993 | 0.84 | GRM5 (0.51) | FFAR1GRM5 | |
| SCHEMBL3346985 | 0.82 | GRM5 (0.42) | FFAR1GRM5OGAPDGFRBKDR | |
| SCHEMBL3346805 | 0.80 | DYRK1A (0.43) | FFAR1GRM5DYRK1AHCRTR1 | |
| SCHEMBL3346980 | 0.80 | GRM5 (0.49) | GRM5PDGFRBKDRCYP3A4 | |
| SCHEMBL3348434 | 0.80 | GRM5 (0.54) | GRM5DYRK1A | |
| SCHEMBL3347295 | 0.80 | GRM5 (0.48) | GRM5DYRK1A | |
| SCHEMBL3347261 | 0.80 | GRM5 (0.47) | GRM5 | |
| SCHEMBL3347519 | 0.79 | GRM4 (0.46) | GRM5DYRK1ACYP3A4 | |
| SCHEMBL3346876 | 0.78 | CYP19A1 (0.42) | CYP11B1CYP11B2 | |
| SCHEMBL3351351 | 0.77 | FFAR1 (0.39) | FFAR1GRM5DYRK1AOGAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |