Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 4/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347542 | 0.89 | GPR119 (0.52) | GPR119 | |
| SCHEMBL3344194 | 0.77 | KCNH2 (0.45) | GPR119KCNH2 | |
| SCHEMBL12283407 | 0.77 | GPR119 (0.61) | GPR119KCNH2 | |
| SCHEMBL2553645 | 0.77 | GPR119 (0.61) | GPR119KCNH2 | |
| SCHEMBL3343438 | 0.76 | GPR119 (0.58) | GPR119 | |
| SCHEMBL3340657 | 0.75 | GPR119 (0.60) | GPR119 | |
| SCHEMBL3346737 | 0.73 | GPR119 (0.49) | GPR119 | |
| SCHEMBL3342662 | 0.72 | GPR119 (0.53) | GPR119 | |
| SCHEMBL2553530 | 0.72 | GPR119 (0.61) | GPR119 | |
| SCHEMBL12283376 | 0.72 | GPR119 (0.61) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |