Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.58 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342852 | 0.82 | GPR119 (0.65) | GPR119GPR183CYP3A4CYP2C19 | |
| SCHEMBL2570249 | 0.82 | GPR119 (0.60) | GPR119GPR183CYP3A4CYP2C19 | |
| SCHEMBL12282735 | 0.82 | GPR119 (0.60) | GPR119GPR183CYP3A4CYP2C19 | |
| SCHEMBL14634214 | 0.79 | GPR119 (0.59) | GPR119GPR183CYP3A4CYP2C19 | |
| SCHEMBL14648401 | 0.79 | GPR119 (0.59) | GPR119GPR183CYP3A4CYP2C19 | |
| SCHEMBL14634213 | 0.79 | GPR119 (0.59) | GPR119GPR183CYP3A4CYP2C19 | |
| SCHEMBL3375030 | 0.79 | GPR119 (0.40) | GPR119GPR183CYP3A4CYP2C19 | |
| SCHEMBL3347542 | 0.76 | GPR119 (0.52) | GPR119 | |
| SCHEMBL3348728 | 0.76 | GPR119 (0.47) | GPR119 | |
| SCHEMBL19434212 | 0.75 | GPR119 (0.62) | GPR119GPR183CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |