Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112757 | 0.90 | KDM4E (0.40) | MEN1KMT2AANPEPALDH1A1KDM4E | |
| SCHEMBL28454918 | 0.77 | HTR2A (0.48) | HTR2AANPEPHTR2C | |
| SCHEMBL9385590 | 0.72 | ACP3 (0.48) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL29037871 | 0.72 | MAOA (0.39) | HTR2AANPEPRAB9AGAAALDH1A1 | |
| SCHEMBL30150914 | 0.72 | IDO1 (0.44) | ACP3MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL2115194 | 0.72 | IDO1 (0.44) | ACP3MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28769170 | 0.71 | MAOA (0.38) | HTR2AANPEPRAB9AGAAALDH1A1 | |
| SCHEMBL8901794 | 0.71 | ACP3 (0.47) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL7124003 | 0.71 | ACP3 (0.47) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL948086 | 0.69 | ACP3 (0.46) | ACP3RETHTR2AANPEPCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |