Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028761 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL11794549 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL29314964 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL5956557 | 0.97 | — | — | |
| SCHEMBL31021559 | 0.92 | THRB (0.41) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL28983025 | 0.91 | ALDH1A1 (0.43) | ALDH1A1HTTTHRBTDP1HPGD | |
| SCHEMBL5344 | 0.91 | — | — | |
| SCHEMBL25829986 | 0.89 | MEN1 (0.44) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL29928454 | 0.89 | MEN1 (0.44) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL18544635 | 0.89 | MEN1 (0.44) | ALDH1A1HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120998-A1 | CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-05-13 | — | — | US | disclosed |