Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 6/20 | 0.47 |
| ▸ | F7 | P08709 | 11/20 | 0.47 |
| ▸ | F3 | P13726 | 10/20 | 0.47 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.41 |
| ▸ | F11 | P03951 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362059 | 0.93 | F9 (0.40) | F9F7F3F10F2 | |
| SCHEMBL335340 | 0.87 | F9 (0.46) | F9F7F3F10F2 | |
| SCHEMBL335522 | 0.86 | F9 (0.53) | F9F7F3F10F11 | |
| SCHEMBL335724 | 0.84 | F7 (0.50) | F9F7F3F10F2 | |
| SCHEMBL336483 | 0.84 | F9 (0.54) | F9F7F3F10F11 | |
| SCHEMBL335697 | 0.83 | F7 (0.52) | F9F7F3F10F2 | |
| SCHEMBL334902 | 0.81 | F9 (0.49) | F9F7F3F10F2 | |
| SCHEMBL334912 | 0.81 | F7 (0.40) | F9F7F3 | |
| SCHEMBL335996 | 0.81 | F9 (0.49) | F9F7F3F10F2 | |
| SCHEMBL335786 | 0.81 | F9 (0.51) | F9F7F3F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |