SCHEMBL362059 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	F9	P00740	5/20	0.40

▸	F7	P08709	4/20	0.39

▸	F3	P13726	4/20	0.39

▸	HDAC1	Q13547	3/20	0.39

▸	KMT2A	Q03164	2/20	0.38

▸	MEN1	O00255	1/20	0.38

▸	NPC1	O15118	1/20	0.37

▸	ROCK2	O75116	5/20	0.36

▸	ROCK1	Q13464	2/20	0.36

▸	F10	P00742	2/20	0.36

▸	F2	P00734	1/20	0.35

▸	F11	P03951	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL334954	0.93	F9 (0.47)	F9F7F3ROCK2ROCK1
SCHEMBL335265	0.86	F9 (0.45)	F9F7F3HDAC1NPC1
SCHEMBL334912	0.81	F7 (0.40)	F9F7F3HDAC1KMT2A
SCHEMBL335437	0.81	F10 (0.46)	F9F7F3HDAC1KMT2A
SCHEMBL334986	0.81	MAPT (0.44)	F9F7F3KMT2AMEN1
SCHEMBL335037	0.80	F9 (0.55)	F9F7F3KMT2AMEN1
SCHEMBL335340	0.80	F9 (0.46)	F9F7F3F10F2
SCHEMBL335522	0.80	F9 (0.53)	F9F7F3NPC1ROCK2
SCHEMBL335724	0.78	F7 (0.50)	F9F7F3ROCK1F10
SCHEMBL335901	0.77	F10 (0.47)	F9F7F3ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8097758-B2	Isoserine derivatives for use as coagulation factor IXa inhibitors	SANOFI-AVENTIS (FR)	2012-01-17	—	—	US	claimed