Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.38 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335599 | 0.88 | RAB9A (0.44) | F7F3ACP1TYMSKMT2A | |
| SCHEMBL335890 | 0.87 | ACP1 (0.40) | F7F3ACP1TYMSKMT2A | |
| SCHEMBL335501 | 0.85 | NPC1 (0.43) | F7F3ACP1TYMSRAB9A | |
| SCHEMBL335570 | 0.84 | PIN1 (0.47) | ACP1RAB9AMAPTABL1FABP6 | |
| SCHEMBL335286 | 0.84 | ACP1 (0.42) | F7F3ACP1TYMSKMT2A | |
| SCHEMBL15282212 | 0.84 | ACP1 (0.46) | F7F3ACP1KMT2AMEN1 | |
| SCHEMBL15282285 | 0.84 | ACP1 (0.46) | F7F3ACP1KMT2AMEN1 | |
| SCHEMBL335244 | 0.82 | MAPT (0.41) | ACP1KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL336014 | 0.82 | ABL1 (0.41) | F7F3ACP1TYMSSMN1; SMN2 | |
| SCHEMBL336367 | 0.82 | MAPT (0.47) | F7ACP1TYMSRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |