SCHEMBL335012

SCHEMBL335012

COc1ccccc1C(C)N1CCNCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 9/20 0.54
SLC6A4 P31645 9/20 0.54
KCNH2 Q12809 6/20 0.54
CYP2D6 P10635 4/20 0.54
HTR3A P46098 2/20 0.54
HTR3E A5X5Y0 1/20 0.54
HTR3B O95264 1/20 0.54
ADRB1 P08588 1/20 0.54
DRD2 P14416 1/20 0.54
CYP2C19 P33261 1/20 0.54
DRD3 P35462 1/20 0.54
HTR6 P50406 1/20 0.54
HTR3D Q70Z44 1/20 0.54
HTR3C Q8WXA8 1/20 0.54
SIGMAR1 Q99720 1/20 0.54
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
SLC6A3 Q01959 5/20 0.52
HTR7 P34969 4/20 0.52
TACR1 P25103 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31464112 1.00 SLC6A2 (0.54) SLC6A2SLC6A4KCNH2CYP2D6HTR3A
SCHEMBL11164684 0.86 SLC6A2 (0.56) SLC6A2SLC6A4KCNH2CYP2D6SLC6A3
SCHEMBL8963904 0.85 OPRD1 (0.56) SLC6A2SLC6A4KCNH2CYP2D6HTR3A
SCHEMBL11886645 0.84 KDM4E (0.49) CYP2D6MAPTCHRM2CHRM1
SCHEMBL13553399 0.83 KDM4E (0.51) CYP2D6MAPT
SCHEMBL13553401 0.80 P4HB (0.52) CYP2D6ADRB1CYP2C19LMNAMAPT
SCHEMBL27950315 0.80 MGAM (0.41) SLC6A2SLC6A4KCNH2CYP2D6HTR3A
SCHEMBL3453995 0.80 SLC6A2 (0.61) SLC6A2SLC6A4KCNH2CYP2D6HTR3A
SCHEMBL4713219 0.80 SLC6A4 (0.41) SLC6A2SLC6A4KCNH2CYP2D6HTR3A
SCHEMBL14371957 0.80 SLC6A4 (0.41) SLC6A2SLC6A4KCNH2CYP2D6HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
WO-2024043334-A1 NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION 富士フイルム株式会社 2024-02-29 WO disclosed
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN disclosed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US disclosed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP disclosed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
EP-1985620-A1 10a-AZALIDE COMPOUND TAISHO PHARMACEUTICAL CO., LTD (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 SLC6A2 4677/4885SLC6A4 4401/4885KCNH2 2875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.