SCHEMBL335038

SCHEMBL335038

COc1ccc(C(C)=O)c(O)c1OC

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.73
TDP1 Q9NUW8 3/20 0.73
GAA P10253 1/20 0.50
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
KDM4E B2RXH2 4/20 0.49
LMNA P02545 3/20 0.49
HSD17B10 Q99714 3/20 0.49
HTT P42858 1/20 0.48
HPGD P15428 3/20 0.47
MAPK1 P28482 3/20 0.46
CYP3A4 P08684 2/20 0.46
RECQL P46063 1/20 0.45
ALOX15 P16050 1/20 0.45
TUBB1 Q9H4B7 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405531 1.00 MAPT (0.73) MAPTTDP1GAAALDH1A1MEN1
SCHEMBL27713896 0.86 MAPT (0.76) MAPTTDP1ALDH1A1KDM4ELMNA
SCHEMBL28805223 0.86 MAPT (0.56) MAPTTDP1GAAALDH1A1MEN1
2-Hydroxy-3,4-Dimethoxybenzoic Acid SCHEMBL419244 0.85 MAPT (1.00) MAPTTDP1ALDH1A1KDM4ELMNA
SCHEMBL3043734 0.84 MAPT (0.61) MAPTTDP1GAAALDH1A1KDM4E
SCHEMBL1421887 0.84 ALDH1A1 (0.59) MAPTTDP1GAAALDH1A1MEN1
SCHEMBL29700534 0.84 MAPT (0.61) MAPTTDP1GAAALDH1A1KDM4E
SCHEMBL30069060 0.84 ALDH1A1 (0.59) MAPTTDP1GAAALDH1A1MEN1
SCHEMBL23121012 0.83 MAPT (0.53) MAPTTDP1GAAALDH1A1KDM4E
SCHEMBL29996551 0.83 MAPT (0.53) MAPTTDP1GAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
EP-4549424-A1 NEW LITHIUM EXTRACTING AGENT AND LIQUID ORGANIC MIXTURE THEREOF, AND METHOD FOR EXTRACTING LITHIUM BY MEANS OF EXTRACTION Beijing Salt Lake Technology Development Company Limited (CN) 2025-05-07 EP disclosed
CN-117603219-A P-glycoprotein inhibitor and preparation method and application thereof 浙江大学 2024-02-27 CN disclosed
CN-117534556-A Novel lithium extractant, liquid organic mixture thereof and method for extracting lithium by extraction 北京索特莱克科技发展有限公司 2024-02-09 CN disclosed
WO-2024027447-A1 NEW LITHIUM EXTRACTING AGENT AND LIQUID ORGANIC MIXTURE THEREOF, AND METHOD FOR EXTRACTING LITHIUM BY MEANS OF EXTRACTION 北京索特莱克科技发展有限公司 2024-02-08 WO disclosed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN disclosed
CN-115040497-A Application of paeonol derivative in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-09-13 CN disclosed
CN-110498784-B Nobiletin derivatives or pharmaceutically acceptable salts thereof, and preparation method and application thereof 广东克冠达医药科技有限公司 2022-06-14 CN disclosed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN disclosed
EP-3831821-A1 COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF Shaanxi Micot Technology Limited Company (CN) 2021-06-09 EP disclosed
WO-2002074036-A2 SUBSTITUTED BENZOPYRANONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-09-26 WO disclosed
US-20020058700-A1 Ion channel modulating agents NEUROSEARCH A/S (DK) 2002-05-16 US disclosed
EP-1133467-A1 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2001-09-19 EP disclosed
EP-1109800-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LIMITED (KR) 2001-06-27 EP disclosed
WO-2000034228-A1 ION CHANNEL MODULATING AGENTS NEUROSEARCH A/S (DK) 2000-06-15 WO disclosed
WO-2000012496-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LTD. (KR) 2000-03-09 WO disclosed
US-5371220-A Bicyclo-heterocyclic intermediates for cephalosporin compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-12-06 US disclosed
US-5232918-A Bactericides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-08-03 US disclosed
US-5019570-A Antibioics IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058700-A1 Ion channel modulating agents KCNN4, KCNN1, KCNJ2 MAPT 3687/4885TDP1 3882/4885GAA 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.