SCHEMBL1421887

SCHEMBL1421887

COc1ccc(C(C)=O)c(OC)c1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
MAPT P10636 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
KDM4E B2RXH2 1/20 0.51
LMNA P02545 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TUBB1 Q9H4B7 3/20 0.49
PDE4D Q08499 2/20 0.49
GAA P10253 1/20 0.49
HTT P42858 1/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP1B1 Q16678 1/20 0.46
PKM P14618 1/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30069060 1.00 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL20118893 0.87 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL9726919 0.85 MAPT (0.58) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL29405531 0.84 MAPT (0.73) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL5144939 0.84 HTT (0.51) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL10740410 0.84 LMNA (0.56) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL335038 0.84 MAPT (0.73) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL4913002 0.83 MAPT (0.56) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL102827 0.83 MAPT (0.72) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL29184862 0.83 PDE4D (0.58) ALDH1A1MEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250113823-A1 Arthropod Control Compositions FIRMENICH SA (CH) 2025-04-10 US claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
CN-115524437-B Method for judging origin of domestic and foreign flos caryophylli based on GC-MS 云南中烟工业有限责任公司 2024-07-05 CN claimed
CN-115524436-B Method for distinguishing clove at different production places at home and abroad 云南中烟工业有限责任公司 2024-06-14 CN claimed
WO-2024084006-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2024-04-25 WO claimed
WO-2023139053-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2023-07-27 WO claimed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
CN-115572255-A Preparation method of chalcone compound 无锡捷化医药科技有限公司 2023-01-06 CN claimed
CN-115524437-A GC-MS-based method for judging producing area of flos caryophylli at home and abroad 云南中烟工业有限责任公司 2022-12-27 CN claimed
CN-115524436-A Method for distinguishing clove in different producing areas at home and abroad 云南中烟工业有限责任公司 2022-12-27 CN claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
US-20250228795-A1 ESTROGENIC COMPOUNDS AND METHODS OF USE IATERION, INC. 2025-07-17 US disclosed
US-20250170111-A1 PYRIDINE BASED CHALCONE ANALOGS AS THERAPEUTIC AGENTS AND USE THEREOF QATAR UNIVERSITY (QA) 2025-05-29 US disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed
EP-0326379-A2 Therapeutic agent for liver disease and piperazine derivatives NIPPON CHEMIPHAR CO., LTD. (JP) 1989-08-02 EP disclosed
US-4436752-A ANTISECRETORY, ANTIULCER ROUSSEL UCLAF (FR) 1984-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170111-A1 PYRIDINE BASED CHALCONE ANALOGS AS THERAPEUTIC AGENTS AND USE THEREOF HCCS, PDXK, NOD1 ALDH1A1 3106/4885MEN1 3589/4885KMT2A 4417/4885
US-20250113823-A1 Arthropod Control Compositions AGO2, EXOSC9, C5 ALDH1A1 3700/4885MEN1 3288/4885KMT2A 2076/4885
US-20250228795-A1 ESTROGENIC COMPOUNDS AND METHODS OF USE ESR1, ESR2, CYP19A1 ALDH1A1 3619/4885MEN1 1634/4885KMT2A 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.