Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346380 | 1.00 | MGLL (0.51) | MGLLDRD2DRD3OPRM1OPRD1 | |
| SCHEMBL3346378 | 1.00 | MGLL (0.51) | MGLLDRD2DRD3OPRM1OPRD1 | |
| SCHEMBL18446074 | 0.87 | MGLL (0.50) | MGLL | |
| SCHEMBL3346286 | 0.85 | MGLL (0.51) | MGLL | |
| SCHEMBL3350922 | 0.85 | MGLL (0.51) | MGLL | |
| SCHEMBL3346282 | 0.85 | MGLL (0.51) | MGLL | |
| SCHEMBL2435728 | 0.84 | MGLL (0.55) | MGLLDRD2 | |
| SCHEMBL2435729 | 0.84 | MGLL (0.55) | MGLLDRD2 | |
| SCHEMBL20396143 | 0.84 | MGLL (0.54) | MGLLDRD2DRD3 | |
| SCHEMBL20396171 | 0.84 | MGLL (0.54) | MGLLDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058318-A1 | 1-OXA-8-AZASPIRO [4, 5 ] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |