Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346286 | 1.00 | MGLL (0.51) | MGLLESR2ESR1FFAR4OGA | |
| SCHEMBL3350922 | 1.00 | MGLL (0.51) | MGLLESR2ESR1FFAR4OGA | |
| SCHEMBL18446074 | 0.89 | MGLL (0.50) | MGLL | |
| SCHEMBL3346380 | 0.85 | MGLL (0.51) | MGLL | |
| SCHEMBL20397239 | 0.85 | MGLL (0.70) | MGLL | |
| SCHEMBL3346378 | 0.85 | MGLL (0.51) | MGLL | |
| SCHEMBL3350643 | 0.85 | MGLL (0.51) | MGLL | |
| SCHEMBL3346464 | 0.82 | MGLL (0.45) | MGLLFFAR4 | |
| SCHEMBL3346469 | 0.82 | MGLL (0.45) | MGLLFFAR4 | |
| SCHEMBL2424910 | 0.82 | MGLL (0.53) | MGLLESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058318-A1 | 1-OXA-8-AZASPIRO [4, 5 ] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |