SCHEMBL3350823

SCHEMBL3350823

Nc1ccnc2c1ccc1ncccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.60
HSP90AA1 P07900 4/20 0.56
HSP90AB1 P08238 3/20 0.56
MAPT P10636 3/20 0.56
LMNA P02545 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
HTT P42858 1/20 0.56
BLM P54132 1/20 0.56
HIF1A Q16665 1/20 0.56
KDM4E B2RXH2 1/20 0.54
NR4A2 P43354 4/20 0.53
IDO1 P14902 1/20 0.53
PSMB5 P28074 1/20 0.53
SOS2 Q07890 1/20 0.44
CYP3A4 P08684 1/20 0.44
MMP14 P50281 1/20 0.44
APAF1 O14727 1/20 0.43
TDP2 O95551 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1097183 0.81 HSP90AA1 (0.59) NCF1HSP90AA1HSP90AB1MAPTLMNA
SCHEMBL4390960 0.80 NR4A2 (0.57) NCF1HSP90AA1HSP90AB1MAPTMEN1
SCHEMBL3382683 0.79 HSP90AA1 (0.58) NCF1HSP90AA1HSP90AB1MAPTLMNA
SCHEMBL2884972 0.79 HSP90AA1 (0.58) NCF1HSP90AA1HSP90AB1MAPTLMNA
SCHEMBL31301051 0.78 LMNA (0.56) NCF1HSP90AA1HSP90AB1MAPTLMNA
SCHEMBL1149989 0.78 CCR1 (0.61) HSP90AA1HSP90AB1MAPTLMNAMEN1
SCHEMBL28341049 0.78 LMNA (0.56) NCF1HSP90AA1HSP90AB1MAPTLMNA
SCHEMBL2390627 0.78 LMNA (0.56) HSP90AA1HSP90AB1MAPTLMNAMEN1
SCHEMBL169672 0.78 LMNA (0.56) HSP90AA1HSP90AB1MAPTLMNAMEN1
SCHEMBL1997158 0.77 LMNA (0.51) NCF1HSP90AA1HSP90AB1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9573117-B2 Catalyst precursors, catalysts and methods of producing same INSTITUTE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2017-02-21 US disclosed
US-20140099571-A1 CATALYSTS MADE USING THERMALLY DECOMPOSABLE POROUS SUPPORTS INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2014-04-10 US disclosed
EP-2673084-A1 CATALYSTS MADE USING THERMALLY DECOMPOSABLE POROUS SUPPORTS Institut National De La Recherche Scientifique (CA) 2013-12-18 EP disclosed
US-8580704-B2 Catalyst precursors, catalysts and methods of producing same INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2013-11-12 US disclosed
WO-2012107838-A1 CATALYSTS MADE USING THERMALLY DECOMPOSABLE POROUS SUPPORTS INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2012-08-16 WO disclosed
US-20110294658-A1 CATALYST PRECURSORS, CATALYSTS AND METHODS OF PRODUCING SAME INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2011-12-01 US disclosed
WO-2010051619-A1 CATALYST PRECURSORS, CATALYSTS AND METHODS OF PRODUCING SAME INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2010-05-14 WO disclosed